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The Real Cédula prohibits all cultivation of tobacco in the Caribbean.

Date: 1606

TOB
COL
SLA

As tobacco is the primary cash crop for colonizers in the Spanish colonies, there is widespread protest when the Real Cédula is passed. Alongside protests of economic hardship, one of the primary complaints is the perceived necessity of tobacco for pacifying enslaved Africans. Protesters argue that enslaved workers become restless without access to tobacco. The protests will end the prohibition in 1614.